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VER155008 inhibits the proliferation of a variety of human colon and breast tumor cell lines
1H/b35-24+
136194-77-9
2015 Oct 1
α-difluoromethylornithine hydrochloride
SCH-1473759 Size:Solid 10 mg VER155008 inhibits the proliferation ofSCH 1473759 is a potent and selective Aurora A B inhibitor with IC50 sub nanomolar. SCH 1473759 was active against a large panel of tumor cell lines from different tissue origin and genetic backgrounds. SCH 1473759 demonstrated potent mechanism based activity, and activity was shown to be enhanced in combination with taxanes and KSP inhibitors. This information may be useful for optimizing the clinical efficacy of Aurora inhibitors. Product
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