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WD2000-012547 867elusetrag hydrochloride Chemical Name: 4-[(4-{2-[2-(2-{2-[(2S)-2-{[(2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)propanamido]acetyl]pyrrolidin-2-yl]formamido}-3

SKU: 20169933483

4.1
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Description

Chemical Name: 4-[(4-{2-[2-(2-{2-[(2S)-2-{[(2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)propanamido]acetyl]pyrrolidin-2-yl]formamido}-3

2012 for use in adult patients starting HIV treatment for the first time as part of the fixed dose combination known as Stribild

Phase II clinical trials in patients with congestive heart failure

and one mouse dies before the second treatment course

with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1

WD2000-012547 867elusetrag hydrochloride Chemical Name: 4-[(4-{2-[2-(2-{2-[(2S)-2-{[(2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)propanamido]acetyl]pyrrolidin-2-yl]formamido}-3WD2000 012547 is a selective poly(ADP ribose) polymerase (PARP 1) inhibitor with a pKi of 8. 221. Product information CAS Number: 283172 68 9 Molecular Weight: 262. 31 Formula: C17H14N2O Chemical Name: 2 phenyl 3,10 diazatricyclo[6. 4. 1. 0,]trideca 1,4(13),5,7 tetraen 9 one Smiles: O=C1NCCC2C3C1=CC=CC=3NC=2C1C=CC=CC=1 InChiKey: CMVVSYUUFABRBC UHFFFAOYSA N InChi: InChI=1S C17H14N2O c20 17 13 7 4 8 14 15(13)12(9 10 18 17)16(19 14)11 5 2 1 3 6 11 h1

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